Efficient Postoperative Pain Management With Multimodal IV

Benha University100 enrolled

Overview

Postoperative pain remains a prevalent concern despite ongoing improvements in surgical methods and pain management strategies. Opioids, while commonly prescribed, frequently lead to undesirable side effects. Epidural analgesia, though a viable option, carries its risks and complications. Recent research indicates that combining intravenous lidocaine and ketamine can significantly alleviate postoperative pain and decrease the reliance on opioids within the initial 24 hours following surgery. This approach offers a promising alternative with minimal additional adverse effects, suggesting a potential shift in pain management practices.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

100

Conditions

Post Operative Pain

Interventions

Multimodal IV analgesiaDRUG

Multimodal IV analgesia of lidocaine, ketamine and MS

epidural analgesiaDRUG

Opioid-based and epidural analgesia

Eligibility

Sex: ALLMin age: 35 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients were assigned for surgical intervention; * Patients of ASA grade I-III; * Patients were free of exclusion criteria; Exclusion Criteria: * Patients who are not in ASA grade I-III; * Patients who had uncontrolled hypertension and/or diabetes mellitus; * Patients who had uncompensated cardiac, renal, or hepatic diseases; * Patients with coagulopathy, spinal deformity, allergy, or contraindication for the used drugs; * Patients who refused to sign the informed consent were excluded from the study.

Locations (1)

Benha University

Banhā, El Qalyoubia, Egypt

Outcomes

Primary Outcomes

Proportion of patients reporting at least a 50% reduction in pain (measured by Numerical Rating Scale) in post-Operative follow up.

Value of Multimodal injection in Pain Reduction post operatively manifested by recurrence of pain.

Time frame: 3 months

Data from ClinicalTrials.gov

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