The goal of this observational study is to learn about the effect of the occlusion pressure during the first 100 miliseconds (P01) over the extubation failure in participants receiving mechanical ventilation for acute respiratory failure. The main question it aims to answer is: Are high P0.1 values (≥3 cmH2O) measured 30 minutes after starting a spontaneous breathing trial associated with extubation failure in adult patients who were intubated for acute hypoxemic respiratory failure?
Study Type
OBSERVATIONAL
Enrollment
256
Sanatorio Anchorena Recoleta
Buenos Aires, Buenos Aires F.D., Argentina
Extubation failure
Extubation failure is defined as reintubation by day 7. The decision to reintubate a patient will be made by the treating team, who will be blinded to the P0.1 values measured during spontaneus breathing trial.
Time frame: From enrollment to the end of follow-up at day 7
Cut-off point of P01
To identify the best cut-off point of P0.1 to predict extubation failure in adult patients who required invasive mechanical ventilation for acute hypoxemic respiratory failure.
Time frame: From enrollment to the end of follow-up at day 7
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