Erythropoietin Gel Effect on Dental Implant Stability

N/ANot Yet RecruitingNCT06665451

Al-Azhar University24 enrolled

Overview

* Achieving and maintaining long-term osseointegration for dental implants is a key objective in the field of dentistry. The success of osseointegration is influenced by the surface treatment applied to dental implants. Numerous coating techniques have been developed to improve and speed up osseointegration. * The aim of the current study is to assess immediate dental implant stability coated with erythropoietin gel, both clinically and radiographically. * Materials and Methods: We conducted a randomized controlled clinical trial.The sample will include patients demanding immediate implant treatment in the anterior maxilla . Patients will be randomly allocated into the two groups of the study. The group A will be treated with erythropoietin gel coated dental implant immediately after extraction of non restorable teeth in the anterior maxilla . Group B will be treated with non coated dental implant immediately after extraction of non restorable teeth in the anterior maxilla . * The primary outcome variable will be implant stability and the secondary outcome will be crestal marginal bone level and bone density around implants. It will be measured at time of implant placement and reevaluated after 6-months .

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Osseointegration

Interventions

Non coated dental implantsOTHER

Patients with fresh extraction sockets in the anterior maxilla will be treated by non coated immediate implant .

Erythropoietin gel coated implantsOTHER

Patients with fresh extraction sockets in the anterior maxilla will be treated by immediate implant coated by erythropoietin gel.

Eligibility

Sex: ALLMin age: 20 YearsMax age: 50 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * All patients Should have nonrestorable teeth in the anterior maxilla indicated for extraction and seeking implant placement. * Good general periodontal health and maintenance. Exclusion Criteria: * Heavy smokers who smoke more than ten cigarettes per day * Acute infected socket * Ant socket with wall defect. * Pregnency * Local or systemic conditions that will interfere with bone healing (uncontrolled diabetes mellitus or human immune deficiency virus infections, resonance therapy), bone disorders (hyperparathyroidism, osteoporosis, or Paget's disease. * Patients who had subjected to intravenous and/or oral bisphosphonate therapy.

Outcomes

Primary Outcomes

Change in implant stability

Implant stability will be assessed by using ( AnyCheck - Implant Stability Tester ) Utilizes physical tapping technique and dumping capacity analysis to measure implant stability with precision

Time frame: Baseline and after 6 month

Secondary Outcomes

Change in marginal bone level and bone density around implants

To evaluate the amount of marginal bone loss and bone density around osseointegrated implants, all patient will be subjected to Cone beam computed tomography (CBCT) immediate postoperative and after 6 months.