The goal of this observational study is to learn about the anti-inflammatory effects of anesthetics on patients undergoing endovascular coiling of cerebral aneurysm. The main question it aims to answer is: Does sevoflurane or propofol affect the inflammatory response in subarachnoid hemorrhage? Participants already undergoing endovascular coiling of cerebral aneurysm will have their serum levels of inflammatory factors measured.
Study Type
OBSERVATIONAL
Enrollment
80
intravenous anesthetic and inhalation anesthetic
Department of Neurosurgery
Wuhan, Hubei, China
Concentration of interleukin-10
Test the concentration of interleukin-10 of the participants
Time frame: From enrollment to 3 months postoperation
Concentration of interleukin-1
Test the Concentration of interleukin-1 in participants
Time frame: From enrollment to 3 months postoperation
Concentration of interleukin-2
Test the concentration of interleukin-2 in participants
Time frame: From enrollment to 3 months postoperation
Concentration of interleukin-6
Test the concentration of interleukin-6 in participants
Time frame: From enrollment to 3 months postoperation
Concentration of interleukin-8
Test the concentration of interleukin-8 in participants
Time frame: From enrollment to 3 months postoperation
Concentration of tumor necrosis factor
Test the concentration of tumor necrosis factor in participants
Time frame: From enrollment to 3 months postoperation
Concentration of S100B
Test the concentration of S100B in participants
Time frame: From enrollment to 3 months postoperation
length of stay
The time from admission to discharge
Time frame: through study completion, an average of 6 months
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costs
Hospitalization expenses
Time frame: through study completion, an average of 6 months
Glasgow Coma Score
The scores are ranging from 3 to 15. And higher scores mean a betterr outcome .
Time frame: From enrollment to 3 months postoperation