This study will be carried out to compare between the effect of 4%Tulsi gel and 1%Chlorohexidine gel as locally administered agents in the treatment of advanced periodontitis. Clinical parameters measurements, microbiological and radiographic assessment will be performed at base line, one month and 3 months after the intervention.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
24
After scaling and root debridement, 4% of Tulsi gel will be injected in to the sulcus until it over flooded, at base line, then after one month.
After scaling and root debridement, 1% of Chlorhexidine gel will be injected in to the sulcus until it over flooded, at base line, then after one month.
Faculty of Dentistry, Al-Azhar university
Cairo, Egypt
Clinical parameters
Improvement of the clinical attachment loss in millimeters.
Time frame: 3 months after end of treatment
Clinical parameters
Improvement of gingival index.
Time frame: 3 months after end of treatment
Clinical parameters
Improvement of probing depth in millimeters.
Time frame: 3 months after end of treatment
Microbiological assessment
Counting microbial colony of Porphyromonas gingivalis
Time frame: 3 months after end of treatment
Microbiological assessment
Counting microbial colony of Fusobacterium nucleatum
Time frame: 3 months after end of treatment
Microbiological assessment
Counting microbial colony of Tannerella forsythia
Time frame: 3 months after end of treatment
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