Clinical and Radiographic Evaluation of Propolis As a Hemostatic Agent for Pulpotomy of Mature Permanent Molars with Irreversible Pulpitis Using Two Different Dressing Materials

Phase 2Active Not RecruitingNCT06679075

Misr International University60 enrolled

Overview

The goal of this clinical trial is to assess the effectiveness of propolis as a hemostatic agent in pulpotomy for adult permanent molars, compared to sodium hypochlorite (NaOCl). It also examines how bioceramic putty performs against mineral trioxide aggregate (MTA) in vital pulp therapy for cases of irreversible pulpitis. Participants will be divided into four groups (15 patients each): * Propolis + bioceramic putty * Propolis + MTA * Sodium hypochlorite + bioceramic putty * Sodium hypochlorite + MTA The Investigator will record the bleeding time and postoperative pain will be recorded. The researcher will assess the clinical and radiographic outcomes for success at 1, 3, and 6 months.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

Conditions

Irreversible Pulpitis Pulpitis Pulpitis - Irreversible

Interventions

Full pulpotomy using propolis and bioceramic puttyPROCEDURE

Full Pulpotomy for participants with mature adult molars diagnosed with irreversible pulpitis; using Propolis as a hemostatic agent and bioceramic putty as a dressing material

Full pulpotomy using Propolis and MTAPROCEDURE

Full Pulpotomy for participants with mature adult molars diagnosed with irreversible pulpitis; using Propolis as a hemostatic agent and MTA as a dressing material

Full pulpotomy using sodium hypochlorite and bioceramic puttyPROCEDURE

Full Pulpotomy for participants with mature adult molars diagnosed with irreversible pulpitis; using sodium hypochlorite (NaOCl) as a hemostatic agent and bioceramic putty as a dressing material

Full pulpotomy using sodium hypochlorite and MTAPROCEDURE

Full Pulpotomy for participants with mature adult molars diagnosed with irreversible pulpitis; using sodium hypochlorite (NaOCl) as a hemostatic agent and MTA as a dressing material.

Eligibility

Sex: ALLMin age: 20 YearsMax age: 45 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Participants of both genders falling within the age range of 20 to 45 years. * Presence of vital mature permanent molars diagnosed as mild or severe irreversible pulpitis per Wolter's classification. * Confirmation of vital bleeding pulp tissue in all canals following complete pulpotomy. Exclusion Criteria: * Non-vital teeth. * Teeth with Immature roots. * Uncontrolled pulpal bleeding persisting beyond 10 minutes post-application of sodium hypochlorite as a hemostatic agent. * Insufficient bleeding post-pulp exposure, indicative of pulp degeneration.

Locations (1)

Misr International University

Cairo, Obour, Egypt

Outcomes

Primary Outcomes

Clinical and radiographic success rate

Success rate of full pulpotomy procedure using different hemostatic agents and different dressing materials using the clinical and radiographic criteria for success and failure.

Time frame: 1, 3, 6 months

Bleeding time

Recording the bleeding time of different participants during hemostasis.

Time frame: During hemostasis (0-10 minutes)

Secondary Outcomes

Post-operative pain

Recording the post-operative pain using Heft-Parker visual analogue scale Minimum value: None Maximum value: Maximum possible The higher values indicate more post-operative pain

Time frame: 24 hours, 3 days, 1 week

Data from ClinicalTrials.gov

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