Clinical and Radiographic Evaluation of Propolis as a Hemostatic Agent in Full Pulpotomy of Mature Permanent Molars With Irreversible Pulpitis

Misr International University60 enrolled

Overview

The goal of this randomized clinical trial is to assess the effectiveness of propolis as a hemostatic agent in full pulpotomy for mature permanent molars with irreversible pulpitis, compared to sodium hypochlorite (NaOCl). The study also compares how bioceramic putty performs compared to mineral trioxide aggregate (MTA) as pulpotomy dressing materials. Participants will be randomly allocated into four groups (15 patients each) according to the hemostatic agent and dressing material used: * Propolis + bioceramic putty * Propolis + MTA * Sodium hypochlorite + bioceramic putty * Sodium hypochlorite + MTA Bleeding time and postoperative pain will be recorded. Clinical and radiographic success will be evaluated at 1, 3, and 6 months following treatment.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Irreversible Pulpitis

Interventions

Full Pulpotomy for participants with mature adult molars diagnosed with irreversible pulpitis; using Propolis as a hemostatic agent and bioceramic putty as a dressing material

Full pulpotomy using Propolis and MTAPROCEDURE

Full Pulpotomy for participants with mature adult molars diagnosed with irreversible pulpitis; using Propolis as a hemostatic agent and MTA as a dressing material

Full pulpotomy using sodium hypochlorite and bioceramic puttyPROCEDURE

Full Pulpotomy for participants with mature adult molars diagnosed with irreversible pulpitis; using sodium hypochlorite (NaOCl) as a hemostatic agent and bioceramic putty as a dressing material

Full pulpotomy using sodium hypochlorite and MTAPROCEDURE

Full Pulpotomy for participants with mature adult molars diagnosed with irreversible pulpitis; using sodium hypochlorite (NaOCl) as a hemostatic agent and MTA as a dressing material.

Eligibility

Sex: ALLMin age: 20 YearsMax age: 45 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Participants of both genders falling within the age range of 20 to 45 years. * Presence of vital mature permanent molars diagnosed as irreversible pulpitis. * Confirmation of vital bleeding pulp tissue in all canals following complete pulpotomy. Exclusion Criteria: * Non-vital teeth. * Teeth with Immature roots. * Uncontrolled pulpal bleeding persisting beyond 10 minutes post-application of sodium hypochlorite as a hemostatic agent. * Insufficient bleeding post-pulp exposure, indicative of pulp degeneration.

Locations (1)

Misr International University

Cairo, Obour, Egypt

Outcomes

Primary Outcomes

Clinical and radiographic success rate

Success rate of full pulpotomy procedure using different hemostatic agents and different dressing materials using the clinical and radiographic criteria for success and failure.

Time frame: 1, 3, 6 months

Bleeding time

Recording the bleeding time of different participants during hemostasis.

Time frame: During hemostasis (0-10 minutes)

Secondary Outcomes

Post-operative pain

Recording the post-operative pain using Heft-Parker visual analogue scale Minimum value: None Maximum value: Maximum possible The higher values indicate more post-operative pain

Time frame: 24 hours, 3 days, 1 week

Data from ClinicalTrials.gov

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