Prospective multicenter cross-sectional study evaluating ultrasound of the main salivary glands (2 parotid and 2 submandibular) in patients with Sjögren's disease compared with patients with other connective diseases (rheumatoid arthritis (RA), lupus, scleroderma) and control patients (patient with dry syndrome without the above-mentioned autoimmune disease).
This is a non-interventional study involving patients who are routinely monitored for their disease, and who typically benefit from ultrasound of the parotid and submandibular salivary glands as part of their dry mouth syndrome. Recruitment will be facilitated by the fact that these will be "general population" patients with Sjögren's disease, lupus, RA, scleroderma with dry syndrome, and control patient. The study will be conducted over a single visit, including a clinical examination and an ultrasound scan. Ultrasound will not be blinded to the clinic, so we will need only one examiner per center. This is a study in routine care, with no additional costs and no expected constraints. The examination will be carried out as part of their routine follow-up.
Study Type
OBSERVATIONAL
Enrollment
501
CHU Brest
Brest, France
Evaluate the rate of patients with structural anomalies of the salivary glands, for each of three populations
The salivary gland assessment score will be evaluated according to the OMERACT score (0-3) for each group of patients.
Time frame: Baseline
Evaluate the proportion of patients with ultrasound abnormalities in each subgroup.
Evaluate the proportion of patients with B-mode ultrasound abnormalities (0-3) in each subgroup.
Time frame: Baseline
Evaluate the proportion of patients with vascular anomalies in each subgroup
Study of the contribution of Doppler ultrasound to the study of salivary gland vascularization in each subgroup
Time frame: Baseline
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