Current recommendations for protein intake after bariatric surgery are not based on strong scientific evidence. It remains unclear how much protein should be eaten to minimize muscle loss and preserve the metabolism and function of individuals post-bariatric surgery. The objective of this study is to analyze the relationships between changes in body composition, nutrition and protein intake, and muscle function after bariatric surgery to further our understanding of the nutritional needs of patients after bariatric surgery. We intend to recruit around 75 participants, men and women, aged between 18 and 65 years. Participants will be recruited from the Bariatric Surgery Clinic, McGill University Health Center.
Study Type
OBSERVATIONAL
Enrollment
75
Montreal General Hospital (MUHC)
Montreal, Quebec, Canada
RECRUITINGChange in weight
Overall weight loss (kg)
Time frame: Baseline (pre-operation), and at 3-months and 6-months post-operation.
Change in BMI
Height and weight will be measured and combined to report BMI (kg/m\^2).
Time frame: Baseline (pre-operation), and at 3-months and 6-months post-operation.
Change in fat mass
Body composition is measured by dual-energy x-ray absorptiometry.
Time frame: Baseline (pre-operation), and at 3-months and 6-months post-operation.
Change in overall body fat percentage
Body composition is measured by dual-energy x-ray absorptiometry.
Time frame: Baseline (pre-operation), and at 3-months and 6-months post-operation.
Resting Energy Expenditure
Resting energy expenditure will be measured in a fasted state by indirect calorimetry. The volume of oxygen and carbon dioxide and water vapor pressure will be taken into consideration to calculate the resting energy expenditure.
Time frame: Baseline (pre-operation), and at 3-months and 6-months post-operation.
Substrate Oxidation
Substrate oxidation will be measured in a fasted state by indirect calorimetry. The volume of oxygen, carbon dioxide, and water vapor pressure will be taken into consideration to calculate the respiratory exchange ratio.
Time frame: Baseline (pre-operation), and at 3-months and 6-months post-operation.
Nurition and Protein Intake
A 3-day food journal and a 24-hour food recall will measure the nutritional profile (protein intake). A 24-hour urine sample will be used to measure urinary nitrogen concentration.
Time frame: Baseline (pre-operation), and at 3-months and 6-months post-operation.
Hormone and Inflammatory Marker Assays
The inflammatory cytokines, chemokines, and adipokines in blood will be measured using Enzyme-Linked Immunosorbent Assay (ELISA).
Time frame: Baseline (pre-operation), and at 3-months and 6-months post-operation.
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