Chronic low back pain (CLBP) is a prevalent condition causing significant pain, disability, and reduced quality of life. While various treatments like exercise, NSAIDs, and spinal manipulation are recommended, their effectiveness is limited. Epidural steroid injections can provide short-term relief but may not be cost-effective and have associated risks. Dexmedetomidine (DXM) is a selective α2-adrenergic agonist with analgesic properties. It has been used as an adjuvant to anesthetics and analgesics to enhance pain relief and reduce opioid consumption. Using DXM in conjunction with local anesthetics for regional blocks has shown promising results in improving analgesia and functional outcomes.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
150
Dexmedetomidine was injected in dose of 0.25 µg/kg
Dexmedetomidine was injected in dose of 0.5 µg/kg
Dexmedetomidine was injected in dose of 0.75 µg/kg
Dexmedetomidine was injected in dose of 1 µg/kg
2 ml of 1.5% lidocaine and 2 ml of triamcinolone was mixed and provided to all patients as epidural injection
Menoufia University
Shibīn al Kawm, El Menoufia, Egypt
Proportion of patients reporting at least a 50% reduction in pain (measured by Numerical Rating Scale) in post-Operative Follow up for Spine Surgery.
Value of Dexmedetomidine injection in Pain Reduction post operatively manifested by recurrence of pain.
Time frame: 3 months
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