To evaluate the potential usefulness of 18F-S16/T807 positron emission tomography/computed tomography (PET/CT) for the diagnosis of primary and metastatic lesions in various Tau-related disease patients.
Subjects with various Tau-related disease patients underwent 18F-S16/T807 PET/CT either for an initial assessment or for recurrence detection. Lesions uptake was quantified by the maximum standard uptake value (SUVmax). The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy of 18F-S16/T807 PET/CT were calculated.
Study Type
OBSERVATIONAL
Enrollment
500
Each subject receive a single intravenous injection of 18F-S16/T807, and undergo PET/CT or MRI imaging within the specificed time.
The First Affiliated Hospital of University of Science and Technology of China
Hefei, Anhui, China
RECRUITINGTianjin Medical University General Hospital
Tianjin, Tianjin Municipality, China
RECRUITINGStandardized uptake value (SUV)
Standardized uptake value (SUV) of S16/T807 for each target lesion of subject or suspected primary tumor or/and metastasis.
Time frame: 30 days
Diagnostic efficacy
The sensitivity, specificity and accuracy of Tau PET/CT were calculated.
Time frame: 30 days
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