Exploring the Predictive Value of Electroencephalography Features in Perioperative Neurocognitive Disorders Following Cardiovascular Surgery

Beijing Chao Yang Hospital100 enrolled

Overview

To explore the predictive value of Electroencephalography features in Perioperative Neurocognitive Disorders in patients undergoing cardiovascular surgery under general anesthesia

Data was acquired on the ward using a 10-20 system with a standard 32-channel EEG cap and an EEG instrument (BP Company, Gilching, Germany). Patients were tested using cognitive assessment scales before and after surgery. Cognitive levels were assessed 1 day before surgery and 1 week after surgery (7±2 days) using the Montreal Cognitive Assessment (MoCA) . Patients were followed up one month (30±2 days) after surgery using the Telephone version of the Montreal Cognitive Assessment Scale (T-MoCA). Preoperative and postoperative electroencephalography brain network-related indexes (such as cluster coefficient, small world index, etc.) in patients with PND will be included in the analysis.

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

Cardiovascular Surgery Perioperative Neurocognitive Disorders

Interventions

cardiovascular surgeryPROCEDURE

Heart bypass surgery; Heart valve replacement surgery

Eligibility

Sex: ALLMin age: 60 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: 1. Written informed consent 2. undergoing coronary artery bypass surgery or valve replacement surgery under general anaesthesia 3. ASA grade: II-IV 4. older than 60 years 5. Able to complete cognitive function tests Exclusion criteria: 1. history of severe neurological diseases and psychiatric diseases 2. history of drug abuse 3. severe hearing or vision impairment 4. preoperative delirium 5. serious adverse reactions such as cardiac arrest and cardiopulmonary resuscitation during surgery 6. patients undergoing secondary surgery in a short period 7. participation in concurrent clinical trials

Locations (1)

Beijing Chao Yang Hospital

Beijing, Beijing Municipality, China

RECRUITING

Outcomes

Primary Outcomes

The predictive value of preoperative Electroencephalography features in patients with postoperative cognitive dysfunction following cardiovascular surgery

Data was acquired on the ward using a 10-20 system with a standard 32-channel EEG cap and an EEG instrument (BP Company, Gilching, Germany). Patients were tested using cognitive assessment scales before and after surgery. Cognitive levels were assessed 1 day before surgery and 1 week after surgery (7±2 days) using The Montreal Cognitive Assessment (MoCA) . Patients were followed up one month (30±2 days) after surgery using the Telephone version of the Montreal Cognitive Assessment Scale (T-MoCA).

Time frame: 2025.08

Secondary Outcomes

The predictive value of preoperative Electroencephalography features in patients with postoperative delirium following cardiovascular surgery

Postoperative delirium was assessed using the confusion assessment method or the confusion assessment method for the intensive care unit (CAM/CAM-ICU) .

Time frame: 2025.08

Electroencephalography features in patients with postoperative delirium

Electroencephalography was collected in delirium patients one week(7±2 days) after surgery. Postoperative delirium was assessed using the confusion assessment method or the confusion assessment method for the intensive care unit (CAM/CAM-ICU) . Preoperative and postoperative electroencephalography brain network-related indexes (such as cluster coefficient, small world index, etc.) in patients with postoperative delirium will be included in the analysis.

Time frame: 2025.08

Central Contacts

Changwei Wei, doctor

CONTACT

13810678936 changwei.wei@ccmu.edu.cn

Data from ClinicalTrials.gov

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