Bergavit is a product contains bergamot. Bergamot is an endemic plant of the Calabrian region in southern Italy with a unique profile of flavonoids and flavonoid glycosides present in its juice and albedo, its flavonoids was able to reduce serum levels of lipids and ameliorate the thickening of the arteries through modulating enzymatic activities, anti-oxidation, anti-inflammatory mechanisms and inhibition of monocyte activation and proliferation.The primary outcome of the study the assessment of the the hypolipidemic effect of Bergavit. The secondary outcomes are the assessment of: a) the hypoglycemic effect of Bergavit, b) the activity of Bergavit on weight loss, and c) the hepatoprotective activity of Bergavit.
The study duration is 4 months. Subjects will attend clinic visits as follows: * T0: First visit: assessment of all baseline parameters, Beginning of treatment * T2: Second visit: assessment only of LDL level, Total cholesterol, ox-LDL, Triglycerides level, fasting glucose. * T3: Third visit: assessment of all parameters. * T4: Fourth visit: assessment of all parameters, end of the treatment.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Enrollment
120
Chung Shan Medical University
Taichung, Taiwan
The Changes of LDL-C of the Subjects.
A randomized-double blind trial. The values change of LDL-C between before to after 0, 8, 12, 10 \& 16 weeks.
Time frame: 16 weeks
The changes of Cholesterol of the Subjects.
A randomized-double blind trial. The values change of Cholesterol between before to after 0, 8, 12, 10 \& 16 weeks.
Time frame: 16 weeks
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