Calprotectin Levels in Necrotizing Enterocolitis

Ankara Yildirim Beyazıt University59 enrolled

Overview

Necrotizing enterocolitis (NEC) is a serious condition that can affect premature babies, leading to complications like intestinal damage and infection. In our study, we measured specific markers (called calprotectin) in blood and stool to understand how severe NEC is and predict outcomes. We found that these markers were higher in babies with more severe NEC (stage 3), especially in those who needed surgery or sadly did not survive. This information can help doctors detect NEC earlier, understand its severity, and make better decisions for treating affected babies.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Necrotising Enterocolitis Neonatal

Eligibility

Sex: ALLMin age: 3 DaysMax age: 30 Days

Medical Language ↔ Plain English

Inclusion Criteria: before 32 weeks of gestation with a birth weight of ≤1500 grams Exclusion Criteria: Infants whose families did not provide consent and those with congenital anomalies were excluded.

Locations (1)

Ankara Bilkent City Hospital

Ankara, Turkey (Türkiye)

Outcomes

Primary Outcomes

The predictive value of serum and fecal calprotectin levels in necrotising enterocolitis (NEC)

The predictive value of serum and fecal calprotectin levels in assessing NEC severity (stage 2 and stage 3), intestinal perforation, the need for surgery, and mortality.

Time frame: 2 years

Data from ClinicalTrials.gov

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