A U.S. Registry of Eosinophilic Esophagitis Pediatric, Adolescent and Adult Patients Treated With DUPIXENT® As Standard of Care

N/AActive Not RecruitingNCT06693531

Regeneron Pharmaceuticals368 enrolled

Overview

This observational research study is to better understand patients with eosinophilic esophagitis (EoE) who have recently been prescribed DUPIXENT® (dupilumab). The purpose of this research study is to look at how DUPIXENT is used in normal care of patients with EoE. Possible benefits to others include a better understanding of EoE and helping to inform research and clinical trial design leading to treatment decisions in this patient population going forward. Patient questionnaires will measure the following: * How EoE makes one feel * EoE signs and/or symptoms, eg, how difficult it is to swallow * How EoE affects quality-of-life * How EoE impacts aspects of daily life * How EoE symptoms have changed throughout the study

Study Type

OBSERVATIONAL

Enrollment

368

Conditions

Eosinophilic Esophagitis (EoE)

Interventions

dupilumabDRUG

No investigational agents will be provided. Dupilumab will be prescribed as per usual clinical practice and will not be provided by the sponsor.

Medical Language ↔ Plain English

Key Inclusion Criteria: 1. Initiating treatment with DUPIXENT® for EoE according to the USPI 2. Participants aged ≥12 years and caregivers or legal guardians of participants aged \<12 years must be able to understand and complete registry-related questionnaires Key Exclusion Criteria: 1. Patients who have a contraindication to DUPIXENT® according to the USPI 2. Treatment with DUPIXENT® within the 6 months prior to the screening assessment 3. Participation in an ongoing interventional study on or within 6 months of the baseline assessment. Once enrolled in registry, participation is allowed in other ongoing studies (at the discretion of the registry investigator) NOTE: Other protocol defined inclusion/exclusion criteria apply

Locations (54)

Phoenix Childrens Hospital

Phoenix, Arizona, United States

Arizona Digestive Health/GI Alliance

Sun City, Arizona, United States

Arkansas Childrens Hospital

Little Rock, Arkansas, United States

Scripps Clinic

La Jolla, California, United States

University of California Los Angeles (UCLA)

Los Angeles, California, United States