Submerged Vs Non-Submerged Guided Bone Regeneration Simultaneous to Implant Placement.

Inclusion Criteria: * • Men and women over 18 years old. * Patients requiring single-unit implant restoration in any tooth site of the maxilla and mandible in between teeth. * Anticipation of a peri-implant buccal osseous dehiscence by means of a CT imaging (cone-beam computed tomography, CBCT) with a maximum vertical dimension height (VDH) of 50%. * Presence of adjacent teeth. * Presence of antagonist teeth. * Minimum primary stability of 25Ncm. * Non-smokers or light smokers (\< 10 cigarettes per day). * Absence of systemic diseases that could influence the outcome of the therapy (i.e., uncontrolled diabetes mellitus, osteoporosis, biphosphonate medication). * Tooth extraction performed at least 4 months before implant placement. * Good level of oral hygiene (Plaque Index \< 25%) (Löe, 1967) * Written informed consent signed. * Keratinized mucosa of at least 2mm on the buccal and lingual of the implant. Exclusion Criteria: * Implant surgery requiring sinus lift procedure. * Previous bone augmentation at the implant site. * Active periodontal disease. * Acute infection at the rehabilitation site. * Long-term non-steroidal anti-inflammatory drug therapy (3 months). * Lactating females or currently pregnancy. * Severe cognitive or psychiatric disorders. * Unwillingness to return for follow-up examination.