This study aims to investigate the effects of EIT-guided and Pplat-guided Phigh settings on regional ventilation and perfusion in ARDS patients during APRV, while also examining the impact of different Phigh settings on gas exchange, respiratory mechanics, and hemodynamics.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
26
The Phigh level selected for the patients in the Intervention group was the intercept point of cumulated collapse and overdistension percentage curves, providing the best compromise between collapsed and overdistended lung.
Wuhan Union hospital
Wuhan, Hubei, China
RECRUITINGThe effects of Phigh guided by different methods on regional lung ventilation assessed by EIT
Time frame: 1 Hour Post-Intervention
Global inhomogeneity assessed by electrical impedance tomography
Time frame: 1 Hour Post-Intervention
Center of ventilation assessed by electrical impedance tomography
Time frame: 1 Hour Post-Intervention
ventilation/perfusion matching assessed by EIT
Time frame: 1 Hour Post-Intervention
Respiratory system compliance
Tidal volume divided by plateau pressure
Time frame: 1 Hour Post-Intervention
mean arterial pressure
Time frame: 1 Hour Post-Intervention
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