Cardioneuroablation is a novel treatment option for reflex-mediated syncope. It involves thermal destruction of neural tissue in the close proximity of heart using catheter introduced to the heart through vein in the groin. Effectiveness of the procedure is satisfactory, however, in some cases there is a possibility of the re-growth of previously ablated tissue. We aim to investigate whether this process could be traced by measurement of various physiological parameters related to heart rate reactivity. Additionally we intend to reveal whether changes in those parameters over time could influence clinical effeciveness of the procedure.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
12
Ablation of parasympathetic ganglia of the heart
Wroclaw Medical University
Wroclaw, Lower Silesian Voivodeship, Poland
Change in degree of parasympathetic denervation (%)
Time frame: 12 months
Change in heart rate (beats/min)
Time frame: 12 months
Change in heart rate variability (ms)
Time frame: 12 months
Change in cardiac barosensitivity (ms/mmHg)
Time frame: 12 months
Change in hypoxic heart rate response (beats/min SpO2)
Time frame: 12 months
Time to recurrence of syncopal event (days
Time frame: 12 months
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