TGRX-678 Phase I Oral Pharmacokinetic Study

Inclusion Criteria: * Healthy participants, male or female * Age between 18 and 45 (both inclusive) * Body Weight: male ≥ 50 kg, female ≥ 45 kg; Body Mass Index (BMI) between 19.0 and 26.0 kg/m\^2 (both inclusive) * Signing informed concent at own will * Able to communicate with researcher and able to complete study per protocol instruction Exclusion Criteria: * Clinically significant abnormal results in lab test, physical exam or 12-lead electrocardiogram (ECG) test * Positive results for Hepatitis B, Hepatitis C, HIV or Syphilis * QT interval elongation as indicated by 12-lead ECG test during screening period * Use of any medication that could impact CYP3A4 enzyme activities within 30 days prior to Screening period * Use of any medication within 14 days of first dose of the investigational drug * Vaccinated within 30 days of first dose of the investigational drug, or planning to be vaccinated during study * History of instrumental cardiovascular diseases * Received major surgery within 6 months prior to Screening, or with surgical wounds not completely healed * History of any severe disease or conditions that could affect study results per investigator's discretion * History of allergic conditions or is allergic to components of the investigational drug * Having conditions that could affect drug absorption or difficulties to swallow * History of smoking of \>5 cigarettes per day within 3 months prior to screening, or cannot stop tabacco using during study * History of alcohol abuse, or alcohol consumption of \>14 unit alcohol within 3 months prior to screening * History of substance use, or tested positive for drug test during screening * History of specific food (i.e., grapefruit, mango) consumption, or/and large tea/coffee/caffeinated drink/grapefruit product intake of \> 8 cups per day, within 2 weeks prior to first dose * Having special dietary requirement and cannot comply with food requirement of the study * Pregnant or breastfeeding female, or tested positive in pregnancy test * History of unprotected sexual activities within 1 month prior to screening * Having plans for pregnancy during the study and within 6 months after study completion; or not agreeing to take strict contraceptive measures during study and within 6 months after study completion * History of blood loss/ blood donation of ≥ 400 mL within 3 months prior to screening, or planning to donate blood within 1 month after study completion * Any reasons that is deemed unsuitable for study participation as determined by investigator