Computational Fluid Dynamics Predicting Intraprosthetic Thrombus Formation and Progression Following EVAR

Xiangya Hospital of Central South University72 enrolled

Overview

Intraprosthetic thrombus (IPT) formation and its progression to limb graft occlusion (LGO) are significant complications following endovascular aneurysm repair (EVAR). Morphological metrics based on preoperative CTA have limited predictive value for these complications. This study aims to assess the potential of computational fluid dynamics (CFD) in predicting IPT formation and its progression to LGO after EVAR.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Intraprosthetic Thrombus Limb Graft Occlusion

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: 1. Aged 18 and above; 2. Patients undergone endovascular aneurysm repair; 3. Signed informed consent forms, willing to receive treatments. Exclusion Criteria: 1. inflammatory aortic aneurysm; 2. patients diagnosed with connective tissue diseases; 3. patients diagnosed with atrial fibrillation; 4. patients lacking post-operative CTA; 5. Patients who are participating in other clinical projects; 6. Patients are not suitable to participate in this study.

Outcomes

Primary Outcomes

Degree of intraprosthetic thrombus in limb graft

Evaluate the area of thrombus occupying the lumen using postoperative CTA

Time frame: From January 2014 to June 2024

Secondary Outcomes

Disease-related complications

Disease-related complications associated with intraprosthetic thrombus or limb graft occlusion, such as thromboembolic events

Time frame: From January 2014 to June 2024

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.