Observational Study of Travellers Pathologies

Institut Pasteur11,000 enrolled

Overview

Traveling to emerging countries is associated with a significant risk of encountering health issues specific to the destination, such as gastrointestinal and respiratory infections, malaria episodes, and road traffic accidents.These conditions are associated with behavioral, geographical, or environmental risk factors. A better understanding of these factors will enable the development of targeted recommendations to minimize travel related health issues. The main objective of this study is to determine the incidence of pathologies occurring during travel outside the metropolitan territory. Furthermore, two key aspects from a Public Health perspective are associated with travel and the globalization of exchanges: the acquisition of emerging pathogens or pathogens with antimicrobial resistance of concern. To study these two aspects, the EOP study includes two sub-studies called EOP-Arbo and EOP-AMR. * EOP-Arbo : The objective of this sub-study is to determine the risk of contracting an arboviral disease during travel, as well as the factors that may favor infection. For this, blood samples will be collected. * EOP-AMR : The objective of this sub-study is to determine the risk of contracting an antibiotic-resistant bacteria during the trip. For this, faecal samples will be collected.

Study Type

INTERVENTIONAL

Allocation

Purpose

PREVENTION

Masking

NONE

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

1. Inclusion Criteria : 1. For all participants in the EOP study : * Major subject (age ≥ 18) * Owns a smartphone compatible with electronic data collection * Preparing to travel outside mainland France * Affiliated with or covered by Social Security or private insurance * Willing to participate in the EOP study 2. For the EOP-Arbo Sub-study : \- Subject who has consented to participate in the EOP\_Arbo study. 3. For the EOP-AMR Sub-study : * Subject who has consented to participate in the EOP\_AMR study. 2. Exclusion Criteria: 1. For all participants in the EOP study : * Travel duration ≤ 3 days * Travel duration \> 12 months * Person traveling as part of an expatriation without planned movement outside the settlement in the destination country * Person under legal protection or unable to express consent for participation 2. For the EOP-Arbo Sub-study : \- Individuals deemed clinically and/or biologically unfit by the investigator to undergo the blood samples required for the study. 3. For the EOP-AMR Sub-study : * No specific exclusion criteria.

Outcomes

Primary Outcomes

Determine the incidence of pathologies occurring during a travel outside the metropolitan territory.

Number of subjects who developed a pathology during the travel among participants

Time frame: 10 years

Secondary Outcomes

For EOP-Arbo sub-study : Determine the prevalence for the occurrence of an arboviral disease (dengue, chikungunya, Zika) during the travel.

Number of arboviral diseases (dengue, chikungunya, Zika) during the travel among participants

Time frame: 10 years

For EOP-AMR sub-study : Determine the prevalence for the acquisition of multi-resistant bacteria (MRB) during the travel.

Proportion of subjects with multi-resistant bacteria acquired during the travel

Time frame: 10 years

Observational Study of Travellers Pathologies

Overview

Conditions

Interventions

Eligibility

Locations (1)

Outcomes

Primary Outcomes

Secondary Outcomes

Central Contacts