Cardiopulmonary exercise testing (CPET) is considered to be a gold standard in pre-operative risk assessment and stratification of high risk patients scheduled for major surgery. Surprisingly, only a limited number of studies examined the prognostic role of CPET in cardiothoracic surgery. This is in contrast with rather poor discriminating quality of cardiovascular surgery risk scores and predominantly elderly cardiovascular surgery patients, with significant comorbidity and high degree of frailty. Recently, CPET was shown feasible in coronary artery bypass grafting surgery candidates. Additionally, the rest parameter, which is the partial pressure of end-tidal carbon dioxide (PETCO2) and a submaximal exercise parameter (the VE/VCO2 slope) with good prognostic utility across multiple respiratory exchange ratio values), has been shown to predict mortality and post-operative complications. Whether these rest and submaximal exercise parameters can be used to predict postoperative complications in cardiovascular surgery patients is yet to be determined.
Study Type
OBSERVATIONAL
Enrollment
130
Subjects will undergo pre-operative cardiopulmonary exercise testing.
Centre of Cardiovascular and Transplantation Surgery
Brno, Czech Republic, Czechia
RECRUITINGSt. Anne's University Hospital in Brno
Brno, Czech Republic, Czechia
ACTIVE_NOT_RECRUITINGpost-operative pulmonary complications
pneumonia, atelectasis, respiratory failure, ARDS
Time frame: within 30 post-operative days
post-operative cardiovascular complications
new arrhythmias (atrial fibrillation, supraventricular tachycardia, etc.), myocardial infarction/minimal myocardial lesion, hypotension, heart failure, pulmonary edema, pulmonary embolism, cardiopulmonary resuscitation
Time frame: within 30 post-operative days
Hospital and Intensive care length of stay
Hospital and Intensive care length of stay
Time frame: within 30 post-operative days
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