This study explores whether recurrent breast cancer can be safely treated with breast-conserving surgery and repeated radiation therapy in cases where patients have previously undergone radiation. Traditionally, recurrent breast cancer has been treated by removing the entire breast. However, recent research has shown that in certain situations, it may be possible to preserve the breast. The study will collect data on the safety of this treatment approach and its effects on patients. The treatment follows standard breast cancer care practices, involving 30 patients from Helsinki and Turku University Hospitals. Patients are carefully selected based on specific criteria, such as tumor size, localization, and prior treatment history. Special attention is given to the planning of radiation therapy and surgical techniques. The goal is to develop new treatment strategies that allow breast preservation even in cases of recurrent breast cancer, providing patients with high-quality and individualized care.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
60
The patients will undergo repeat Breast Conserving Surgery and Radiotherapy
The patients will undergo mastectomy
Helsinki University Hospital
Helsinki, Finland
RECRUITINGTurku University Hospital
Turku, Finland
RECRUITINGA treatment-limiting radiation therapy complication.
Any complication related to radiation therapy, that would limit completing the radiotherapy
Time frame: From the beginning of the radiotherapy until 30 days after finishing the therapy
Quality of life (Breast-Q scale)
Patients are asked to complete a quality of life questionnaire (Breast-Q) before the surgery and at 3 months, 1 year, 3 years, and 5 years after the surgery.
Time frame: 5 years from surgery
Second Breast Cancer Recurrence
The patients are surveilled for second breast cancer recurrence
Time frame: 5 years from surgery
Secondary malignancies
The patients are surveilled for any other secondary malignancy than breast cancer
Time frame: 5 years
Quality of life (EORTC QLQ-C30)
Patients are asked to complete a quality of life questionnaire (EORTC QLQ-C30) before the surgery and at 3 months, 1 year, 3 years, and 5 years after the surgery
Time frame: 5 years from the operation
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.