Overview of Botriomycoma in Children with a Central Line: Epidemiology, Risk Factors, Treatments

N/AActive Not RecruitingNCT06708689

Hospices Civils de Lyon240 enrolled

Overview

Botriomycomas are frequent benign tumors in children. Their appearance on the central catheter orifice is a known event in clinical practice, but one that has been little studied. This lesion could lead to changes in pathways and an increase in the number of sepsis events, which would promote thrombosis and thus depletion of venous capital in patients who have been dependent on a central line for many years. This study is a pilot study which will enable us to better identify the risk factors for the development of such a tumour, and to take stock of the different treatments used and their respective efficacy.

Study Type

OBSERVATIONAL

Enrollment

240

Conditions

Home Parenteral Nutrition Intestinal Failure Central Line Botriomycoma Infection Sepsis Antibiotics

Medical Language ↔ Plain English

Inclusion Criteria: * home parenteral nutrition patients * never diagnosed with an episode of botriomycoma on their central line * 0 to 18 years of age at diagnosis Exclusion Criteria: * Botriomycoma more than 10 years old at time of data collection (or lack of data) * Patient over 18 years of age * Not on home parenteral nutrition patients

Outcomes

Primary Outcomes

Appearance of Botryomycoma

genetic characteristics (origin, phototype), local factors (mechanical, infectious), and general factors (history of sepsis).

Time frame: From first diagnosis through a follow-up period of 2 years.

Recurrence of Botryomycoma

analyze risk factors for recurrence and evolution under different treatments.