This study intends to prove the clinical effect of Zhidong Huoxue Tongyu capsule in the treatment of stable angina pectoris with qi deficiency and blood stasis syndrome from the perspective of TCM syndrome differentiation and treatment. To detect metabolites in serum, urine and feces of patients with stable angina pectoris syndrome of qi deficiency and blood stasis by LC-MS metabolomics technology. Compared with normal control group, differential metabolites were found to provide molecular basis for the diagnosis of the disease. Metabolomics technology based on LC-MS was used to analyze the metabolites in serum, urine and feces before and after the treatment of Zhulong Huoxue Tongyu capsule in stable angina pectoris with qi deficiency and blood stasis syndrome. To provide laboratory evidence for Zhilong Huoxue Tongyu capsule in the treatment of stable angina pectoris with qi deficiency and blood stasis syndrome.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
230
Placebo Comparator
Zhilong Huoxue Tongyu capsule
Affiliated Hospital of Traditional Chinese Medicine of Southwest Medical University
Luzhou, Sichuan, China
TCM syndrome integral scale
Time frame: From enrollment to 60 days after treatment
CCS angina grading
Time frame: From enrollment to 60 days after treatment
The number of angina attacks
Time frame: From enrollment to 60 days after treatment
Nitroglycerin usage
Time frame: From enrollment to 60 days after treatment
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