Biomarkers in EV Associated With Marrow Adiposity in Anorexia

Inclusion Criteria: For AN group: * Diagnosis of active AN according to DSM-5 criteria * BMI of less than 17kg/m2 * Present amenorrhoea in the 3 months prior to the start of the study. For AN-R group: * Achieved weight gain of more than 85%. * Normal menstruation in the last 3 months. For Control group: * Population of the same age and gender as the AN and AN-R groups. * If pubertal population, presenting a chronological age of ± 2 years. * Normal menstruation * Normal BMI (\>18.5 kg/m2) * No presence of previous dietary transtrons. Exclusion Criteria: * Not receiving oestrogens, contraceptives or glucocorticoids in the 3 months prior to the start of the study. * Not to suffer from chronic diseases, such as diabetes, pathologies affecting the bone system or thyroid function. * Do not take calcium or vitamin supplements.