Venous Ultrasound Guided Organ Decongestion in Patients Hospitalized with Acute Decompensated Heart Failure

Change in NT-ProBNP

Change in biomarker NT-ProBNP in serum.

Time frame: From the time of enrollment until hospital discharge, typically ranging from 3 to 21 days.

Change in estimated renal glomerular filtration rate

Estimated glomerular filtration rate (eGFR) is calculated based on serum creatinine, age and gender.

Time frame: From the time of enrollment until hospital discharge, typically ranging from 3 to 21 days.

Change in urine albumin creatinine ratio

Urine albumin creatinine is measured in spot urine sample.

Time frame: From the time of enrollment until hospital discharge, typically ranging from 3 to 21 days.

Change in symptoms

Participants are asked to grade their symptoms using a 7-point Likert scale ranging from 1 to 7, where 1 indicates markedly better, 4 indicates no change, and 7 indicates markedly worse. Additionally, participants are asked to report their general condition and level of dyspnea on a Visual Analogue Scale (VAS) where 0 is negative and 100 is positive.

Time frame: From the time of enrollment until hospital discharge, typically ranging from 3 to 21 days.

Length of hospitalization

Number of days from inclusion to discharge from hospital.

Time frame: From the time of enrollment until hospital discharge, typically ranging from 3 to 21 days.

Achieved dosage of HF medications at discharge

Current heart failure medication compared to target dose in the national recommendations of HF-patient population.

Time frame: From the time of enrollment until hospital discharge, typically ranging from 3 to 21 days.

Safety

Rates of symptomatic hypotension,worsening renal function, arrhythmias, severe metabolic alkalosis and electrolyte disturbances

Time frame: From the time of enrollment until hospital discharge, typically ranging from 3 to 21 days.