This trial is conducted in China. The aim of the trial is to evaluate the efficacy and safety of BGM0504 versus semaglutide as add-on to metformin and/or sulfonylureas in patients with type 2 diabetes
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
537
Experimental: 5 mg BGM0504 5 milligrams (mg) BGM0504 administered subcutaneously (SC) once a week.
Experimental: 10 mg BGM0504 10 mg BGM0504 administered SC once a week.
Active Comparator: 1 mg Semaglutide 1 mg semaglutide administered SC once a week
Peking University People's Hospital
Beijing, Beijing Municipality, China
RECRUITINGChange From Baseline in Hemoglobin A1c (HbA1c)
Change from baseline in HbA1c after 32 weeks of treatment.
Time frame: Week 0 to Week 32
Change From Baseline in Body Weight
Change from baseline in body weight after 52 weeks of treatment.
Time frame: Week 0 to Week 52
Change From Baseline in Hemoglobin A1c (HbA1c)
Change from baseline in HbA1c after 52weeks of treatment.
Time frame: Week 0 to Week 52
Percentage of Participants With HbA1c Target Value of <7%
Percentage of Participants With HbA1c Target Value of \<7% after 52weeks of treatment.
Time frame: Week 0 to Week 52
Percentage of Participants With HbA1c Target Value of <5.7%
Percentage of Participants With HbA1c Target Value of \<5.7%after 52weeks of treatment.
Time frame: Week 0 to Week 52
Change From Baseline in Fasting Serum Glucose
Change from baseline in FPG after 52 weeks of treatment.
Time frame: Week 0 to Week 52
Linong Ji,MD, chief physician, Peking University People's Hospital
CONTACT
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