Open vs. Laparoscopic Surgery for Pediatric Choledochal Cyst

In-Jin Jang72 enrolled

Overview

This is a retrospective cohort study designed to compare the outcomes of open surgery versus laparoscopic surgery in pediatric patients diagnosed with congenital choledochal cyst (CCC). The study includes children who underwent surgery at Guangdong Medical University Affiliated Hospital and Guangzhou Women and Children's Medical Center between January 1, 2010, and September 1, 2024. The aim of this study is to evaluate and compare the surgical outcomes, including surgery duration, intraoperative blood loss, hospital stay, and postoperative complications (e.g., bile leakage and intestinal obstruction), between the two surgical approaches. The data collected from the patient records will be analyzed to identify factors influencing surgical outcomes and to guide future treatment decisions for CCC in pediatric patients.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Congenital Choledochal Cyst Pediatric Surgery Surgical Outcomes Open Surgery Laparoscopic Surgery

Interventions

Eligibility

Sex: ALLMin age: 0 YearsMax age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: Pediatric patients diagnosed with congenital choledochal cyst based on preoperative imaging (e.g., ultrasound, computed tomography（CT）, or magnetic resonance cholangiopancreatography（MRCP)）. Patients who underwent either open surgery (open cyst excision and Roux-en-Y hepaticojejunostomy) or laparoscopic surgery (laparoscopic cyst excision and Roux-en-Y hepaticojejunostomy) for the treatment of congenital choledochal cyst. Informed consent for follow-up obtained from the patient's family or legal guardian. Exclusion Criteria: Patients lacking one or more key outcome measures, including surgery duration, hospital stay, intraoperative blood loss, incidence of postoperative bile leakage, or incidence of postoperative intestinal obstruction. Patients with incomplete clinical data, such as missing sex, age, or other essential demographic information. Patients with coagulation disorders that may interfere with surgery or recovery. Patients with severe comorbidities or immune system disorders that may complicate surgical intervention or recovery. Patients who underwent non-surgical treatment (e.g., endoscopic procedures) for congenital choledochal cyst. Pregnant patients or those who are breastfeeding (if applicable to your study population).

Outcomes

Primary Outcomes

Surgery Duration

The time required to complete the surgical procedure, from the initial incision to the closure of the surgical site. This is measured in minutes and compared between the open surgery and laparoscopic surgery groups

Time frame: Measured intraoperatively, from the initial incision to the closure of the surgical site, at the end of the surgery.

Postoperative Complications

The occurrence of postoperative complications, specifically bile leakage and intestinal obstruction, in patients undergoing either open or laparoscopic surgery. This is measured as a binary outcome (yes/no) and will be compared between the two groups.

Time frame: 30 days post-surgery (for short-term complications)

Intraoperative Blood Loss

The total amount of blood lost during the surgical procedure, measured in milliliters (mL). This will be compared between the two surgical groups (open surgery and laparoscopic surgery).

Time frame: Measured intraoperatively, during the surgery, from the initial incision to the closure of the surgical site.

Hospital Stay

The total number of days the patient stays in the hospital post-surgery until discharge. This is compared between the open surgery and laparoscopic surgery groups.

Time frame: Measured from the day of surgery to discharge, assessed over the duration of hospital stay, up to 30 days post-surgery.