§ The goal of this clinical trial is to assess the effect of periarticular procaine injections combined with physical therapy on joint pain in individuals 65 and older suffering from osteoarthritis of the hip or the knee. The main question it aims to answer is: Is procaine effective in decreasing joint pain? Researchers will compare procaine injections combined with physical therapy to physical therapy only to evaluate whether or not procaine helps decrease joint pain. Participants will: Undergo procaine periarticular injections and physical therapy Assess their symptoms and pain using scales and tests provided
This clinical trial aims to evaluate the safety and efficacy of procaine complex injections in managing pain and improving functional capacity in elderly patients with osteoarthritis in the knee and/or hip. The study enrolled 178 patients aged 65 and older, who were randomly assigned to receive either physical therapy combined with periarticular procaine injections or physical therapy alone. Pain levels were assessed using the Visual Analogue Scale (VAS), and functional capacity was evaluated using the Lequesne Index, Activities of Daily Living (ADL), Instrumental Activities of Daily Living (IADL), and other geriatric assessment tools. Results indicated significant pain reduction and functional improvement in the procaine group, highlighting a safe alternative treatment to surgery for older adults with osteoarthritis.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Enrollment
203
Participants will receive periarticular 5 ml procaine injections targeting painful joints for 10 consecutive days alternating between knee- and/or hip joints
Kinesiotherapy
"Sf. Luca" Chronic Disease Hospital
Bucharest, Romania
Pain Levels
Change in Pain Level on Visual Analogue Scale (VAS)
Time frame: Baseline to Day 10
Functional Improvement
Change in Lequesne Index Score
Time frame: Baseline to Day 10
ADL and IADL Scores
Changes in Activities of Daily Living and Instrumental ADL scores
Time frame: Baseline to Day 10
Geriatric Depression Scale
Change in Depression Symptoms
Time frame: Baseline to Day 10
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.