This is a retrospective and prospective study planned to include NSCLC patients with Leptomeningeal metastasis (LM) and treated with antitumor therapy after 2018, from multiple centers such as the First Affiliated Hospital of Guangzhou Medical University, Guangdong Sanjiu Brain Hospital, etc., aiming to establish a database related to the treatment strategies of LM patients, and to evaluate the efficacy (eg. Overall Survival/Time to Failure) and safety of different treatment strategies of LM patients, etc., as well as the significance of concomitant testing in LM patients.
retrospective and prospective study
Study Type
OBSERVATIONAL
Enrollment
1,000
This is a retrospective and observational study. Not Applicable
Guangdong Sanjiu Brain Hospital
Guangzhou, Guangdong, China
RECRUITINGthe First Affiliated Hospital of Guangzhou Medical University
Guangzhou, Guangdong, China
RECRUITINGOverall survival(OS)
Time frame: 6 years
Time to failure(TTF)
Time frame: 6 years
Change in cerebrospinal fluid and metabolic markers during treatment
Time frame: 6 years
Safety during actual clinical treatment
Time frame: 6 years
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