The goal of this observational study is to learn about the amide proton transfer-weighted imaging for rectal cancer response assessment after neoadjuvant therapy. The main question it aims to answer is: • Does amide proton transfer-weighted imaging predict the cancer response before surgery? Participants will underwent amide proton transfer-weighted imaging as part of their regular MRI examination.
Study Type
OBSERVATIONAL
Enrollment
320
Sixth Affiliated Hospital, Sun Yat-sen University
Guangzhou, Guangdong, China
RECRUITINGXinyi People's Hospital
Maoming, Guangdong, China
NOT_YET_RECRUITINGthe area under curve (AUC) of receiver operating characteristic (ROC) curves of models in prediction tumor response
Time frame: From date of baseline MRI to date of preoperative MRI，within 12 months
the specificity of models in prediction tumor response
Time frame: From date of baseline MRI to date of preoperative MRI，within 12 months
the sensitivity of models in prediction tumor response
Time frame: From date of baseline MRI to date of preoperative MRI，within 12 months
the positive predictive value of models in prediction tumor response
Time frame: From date of baseline MRI to date of preoperative MRI，within 12 months
the negative predictive value of models in prediction tumor response
Time frame: From date of baseline MRI to date of preoperative MRI，within 12 months
the accuracy of models in prediction tumor response
Time frame: From date of baseline MRI to date of preoperative MRI，within 12 months
disease-free survival and overall survival
Time frame: From date of enrollement until the date of first documented progression or date of death from any cause, whichever came first, assessed up to 60 months
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