Exercise in Hypoxia and Nitrate Supplementation in Athletes: is the Whole Greater Than the Sum of Its Parts?

University of Trás-os-Montes and Alto Douro30 enrolled

Overview

Determine the combined effect of training in hypoxia and nitrate supplementation on the performance and health of athletes at sea-level and altitude conditions.

Determine the combined effect of training in hypoxia and nitrate supplementation on the performance and health of athletes at sea-level and altitude conditions. It is hypothesized that the combined effect of these interventions will promote an additional performance and health improvement in this population at sea-level and altitude conditions, compared with the single effect.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Hypoxia

Interventions

Nitrate + HypoxiaCOMBINATION_PRODUCT

The combined effect of nitrate supplementation and hypoxia training on both performance and health at sea-level and altitude conditions.

Placebo + HypoxiaDIETARY_SUPPLEMENT

The combined effect of placebo supplementation and hypoxia training on both performance and health at sea-level and altitude conditions.

ControlOTHER

The combined effect of placebo supplementation and normoxia training on both performance and health at sea-level and altitude conditions.

Eligibility

Sex: MALEMin age: 18 YearsMax age: 45 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * trained male subjects, regularly involved in competitive running, cycling and/ or triathlon events (4-5 times per week) in the past five years Exclusion Criteria: * smoking or other chronic issues * using medication or dietary supplements in the last 3 months, or during the duration of the study * being exposed to altitude (≥2000 m) in the last 3 months

Locations (1)

University of Trás-os-Montes e Alto-Douro

Vila Real, Portugal