Short Course Regimen in Low Risk Active Tuberculosis- a Multicenter, Randomized, Active-controlled, Trial

Inclusion Criteria: * Newly diagnosed pulmonary tuberculosis patients combined with any of the following diagnostic conditions: * at least one set of sputum specimens is positive for Mycobacterium tuberculosis culture or TB PCR test; or * pathological and histological findings of typical tuberculosis manifestations; * clinical diagnosis and Physician determines the need for complete anti-tuberculosis treatment * Those who have had tuberculosis in the past and have been cured for at least three years can be included * Aged over 20 years old * Laboratory data at the time of inclusion in the study or within 14 days: * Serum or plasma glutamic acid pyruvate transaminase (ALT) value ≦ three times the upper limit of normal * Serum or plasma total bilirubin ≦ 2.5 times the upper limit of normal * Serum or plasma creatinine ≦ twice the upper limit of normal or creatinine clearance greater than 30 mL/min * Heme ≧7.0 g/Dl * Platelets ≧100,000/mm3 * Patient signs consent form * Patients who agree to join and cooperate with the county and city health bureau's urban treatment plan to ensure medication compliance. Exclusion Criteria: * The acid-fast smear of sputum or respiratory specimen is strongly positive (≥ 2+) * Chest X-ray or lung computed tomography combined with open lesions * Chest X-ray or lung computed tomography shows extensive lesions and the clinician judges that short-term treatment is not suitable * Simultaneous combination of intrapulmonary and extrapulmonary tuberculosis * People who are unable to take oral medications * People who have participated in this research * Have used anti-tuberculosis drugs for more than 14 days * A history of tuberculosis suspected or diagnosed as central nervous system tuberculosis, bone or joint tuberculosis, miliary tuberculosis or tuberculous pericarditis. * Known history of allergy or intolerance to this study drug * Patients with HIV infection, organ transplantation, and chronic renal failure * Long-term use of immunosuppressive drugs, including steroid use \>10mg/day (more than 30 consecutive days in the last three months) * Late exclusion: Mycobacterium tuberculosis is known to be resistant to any one or more of the following drugs: rifampin, isoniazid, ethambutol