Effect of Ultrasound Cavitation on Insulin Resistance in Patients with Central Obesity in Female

Inclusion Criteria: * Female subjects with central obesity. * Female participants aged between 25 to 40 years. * Body Mass Index (BMI) ranged from 30 to 35 kg/m2 as high BMI indicates more obesity and central obesity. * Waist circumference greater than 88 cm, indicative of abdominal obesity. * Diagnosed with insulin resistance (HOMA-IR \> 2.9). * Sedentary lifestyle, defined as engaging in less than 150 minutes of moderate-intensity physical activity per week. * Willingness to provide informed consent and comply with study procedures. Exclusion Criteria: * • Subjects diagnosed with DM (HbA1c more than 6.5%). * History of metabolic disorders such as type 1 diabetes or thyroid disorders. * Subjects with BMI less than 30 kg/m2. * Subjects diagnosed with heart disease, liver as well as kidney diseases. * Subjects who take oral contraceptives. * Subjects with gestational Diabetes. * Pregnant or breastfeeding women were excluded from the study. * Use of weight-loss medications or supplements within the past six months. * Previous surgical procedures for weight loss or body contouring. * Contraindications to ultrasound therapy (e.g., metal implants in the abdomen, active skin infections). * Participation in another clinical trial within the last three months.