This study will investigate how RO7269162 labeled with a carbon tracer (\[14C\]) is absorbed, metabolized, and eliminated by the body after a single dose in healthy male volunteers.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
8
Participants will receive one oral dose of \[14C\]-labeled RO7269162.
ICON Health sciences research center
Groningen, Netherlands
[14C] recovery in urine
Time frame: Up to Day 22 or Day 37
[14C] recovery in feces
Time frame: Up to Day 22 or Day 37
Concentration of [14C] in whole blood
Time frame: Up to Day 22 or Day 37
Plasma concentration of [14C]
Time frame: Up to Day 22 or Day 37
Plasma concentration of RO7269162
Time frame: Up to Day 22 or Day 37
Amount of RO7269162 excreted in urine
Time frame: Up to Day 22 or Day 37
Amount of RO7269162 metabolites in plasma
Time frame: Up to Day 22 or Day 37
Amount of RO7269162 metabolites in blood
Time frame: Up to Day 22 or Day 37
Amount of RO7269162 metabolites excreted in urine
Time frame: Up to Day 22 or Day 37
Amount of RO7269162 metabolites excreted in feces
Time frame: Up to Day 22 or Day 37
Incidence and severity of adverse events
Time frame: Up to Day 22 or Day 37
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