This study aimed to compare the serratus plane block versus the erector spinae plane block with dexmedetomidine added to bupivacaine for acute pain management after breast surgeries.
Approximately 40-60% of breast surgery patients endure severe acute postoperative pain, with over 10% of patients experiencing severe pain for six to twelve months (post-mastectomy pain syndrome). Dexmedetomidine has analgesic properties, which could be related to the stimulation of α2 adrenoceptors, inhibition of nerve conduction through C and Aδ fibers, and the local release of encephalin. Serratus plane block (SPB) is an effective approach for breast surgery analgesia due to its simplicity of delivery, minimal risk of adverse effects, and ability to provide significant pain relief. The erector spinae plane block (ESPB) is one of the emerging regional techniques for managing postoperative pain. ESPB can be given unilaterally during modified radical mastectomy.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
40
Patients received serratus anterior plane block on the operated side with bupivacaine 0.25% plus 0.5 µg/kg dexmedetomidine in 30 ml.
Patients received erector spinae plane block at T5 on the operated side and will receive bupivacaine 0.25% plus 0.5 µg/kg dexmedetomidine in 30 ml.
Kafrelsheikh University
Kafr ash Shaykh, Kafrelsheikh, Egypt
Total dose of pethidine consumption
Patients get 1 g paracetamol IV like clockwork. Salvage absence of pain as bolus IV pethidine at 0.5 mg/kg was managed if NRS \> 3
Time frame: 24 hours postoperatively
Intraoperative fentanyl consumption
In case the cruel blood vessel weight (Outline) or heart rate (HR) went over 20% of pattern values, additional bolus dosages of 0.5 µg/kg IV fentanyl were given.
Time frame: Intraoperatively
Heart rate
Heart rate was measured preoperatively and intraoperatively every 15 minutes until the end of the surgery.
Time frame: Every 15 minutes until the end of the surgery (Up to 2 hours)
Mean arterial pressure
Mean arterial pressure was measured preoperatively and intraoperatively every 15 minutes until the end of the surgery.
Time frame: Every 15 minutes until the end of the surgery (Up to 2 hours)
Degree of pain
Each patient was instructed about postoperative pain assessment with the numeric rating scale (NRS) score. NRS (0 represents "no pain" while 10 represents "the worst pain imaginable"). NRS was assessed at post anesthesia care unit, 1, 2, 6, 12, 18, and 24 hours postoperatively
Time frame: 24 hours postoperatively
Incidence of complications
Incidence of complications such as hypotension, bradycardia, and postoperative nausea and vomiting (PONV) were recorded.
Time frame: 24 hours postoperatively
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