The goal of this clinical trial is to verify the efficacy and safety of pulsed electric field (PEF) treatment of early-stage unreseectable non-small cell lung cancer(NSCLC) patients. The main questions it aims to answer are: * Safety of PEF treatment of early-stage unreseectable NSCLC patients. * Locoregional control of ablated lesions. * Survival and quality of life assessment of early-stage unreseectable NSCLC patients.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
126
PEF Energy ablation of lung tumors
Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine,
Shanghai, China
RECRUITING6-month complete ablation rate
Time frame: 6 months
Technical success rate
Time frame: immediately after the PEF ablation treatment
6-month pulmonary progression-free survival rate
Time frame: 6 months after the first PEF ablation treatment
12-month complete ablation rate
Time frame: 12 months after the first PEF ablation treatment
12-month pulmonary progression-free survival rate
The proportion of subjects with no pulmonary progression (the first ablation lesion maintained no progression, no hilar lymph node metastasis, no new lesions) accounted for the proportion of evaluable subjects who received ablation
Time frame: 12 months after the first PEF ablation treatment
12-month overall survival rate
Time frame: 12 months after the first PEF ablation treatment
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