Refugee Insect Production for Food and Feed: the School Meal Intervention

Change in myeloperoxidase (MPO) over 3 months intervention period

Assessing the effect of the intervention on myeloperoxidase (ng/mL), which is a stool marker for Environmental Enteric Dysfunction (EED). A high value indicates high intestinal inflammation.

Time frame: 3 months

Change in alpha-1-anti-trypsin (AAT) over 3 months intervention period

Assessing the effect of the intervention on alpha-1-anti-trypsin (mg/g) which is a stool marker for Enteric Environemtal Dysfunction ( EED). A high value indicates high intestinal protein loss.

Time frame: 3 months

Change in in Neopterin (NEO) over the 3 months intervention period

Assessing the effect of the intervention on Neopterin ( nmol/L) which is a stool marker for Enteric Environemtal Dysfunction (EED). A high value indicates intestinal inflammation.

Time frame: 3 months

Change in weight over the 3 months intervention period

Assessing the effect of the intervention on weight gain (kg)

Time frame: 3 months

Change in BMI- for- age Z-score over 3 months intervention period

Assessing the effect of the intervention on BMI-for-age Z-score, by combining weight (Kg) and Height (m2) to report BMI (kg/m2) using the cut offs: Overweight: \>+1SD, Obesity: \>+2SD, Thinness: \<-2SD, Severe thinness: \<-3SD

Time frame: 3 months

Change in Height- for-age Z-score over the 3 months intervention period

Assessing the effect of the intervention on height-for-age Z-score values using the cut offs: \< -2 to -3 HAZ moderately stunted, HAZ \< -3 severely stunted

Time frame: 3 months

Change in Weight- for-age Z-score over the 3 months intervention period

Assessing the effect of the intervention on weight-for-age Z-score using the cut offs: -2 to-3 WAZ moderately underweight, WAZ \< -3 severely underweight

Time frame: 3 months

Change in Mid-Upper Arm Circumference (MUAC) over the 3 months intervention period

Assessing the effect of the intervention on the Mid-Upper Arm Circumference in cm using the cut-offs: \<13.5cm severe acute malnutrition, 13.5cm -14.5cm moderate acute malnutrition.

Time frame: 3 months

Change in Subscapular and Triceps skinfold thickness over 3 months intervention period

Assessing the effect of the intervention on subscapular and triceps skinfold thickness measured in mm.

Time frame: 3 months

Change in waist circumference measurement over 3 months intervention period

Assessing the effect of the intervention on waist circumference measured in cm.

Time frame: 3 months

Change in fat mass over the 3 months intervention period

Assessing the effect of the intervention on fat mass measured in kgs using deuterium dilution method and bioimpedance analyzer. Low fat mass indicates healthier body composition.

Time frame: 3 months

Change in fat free mass over the 3 months intervention period

Assessing the effect of the intervention on fat free mass measured in kg using deuterium dilution method and bioimpedance analyzer. A high fat free mass indicates high muscle mass and healthier body composition.

Time frame: 3 months

Change in fat mass index over the 3 months intervention period

Assessing the effect of the intervention on fat mass index measured in kg/m2, using deuterium dilution method and bioimpedance analyzer. Low fat mass index indicates a healthier body composition.

Time frame: 3 months

Change in fat free mass index over 3 months intervention period

Assessing the effect of the intervention on fat free mass index ( FFMI) measured in kg/m2 using deuterium dilution method and bioimpedance analyzer. A high fat free mass index indicates high muscle mass and healthier body composition

Time frame: 3 months

Change in C- reactive protein (CRP) over the 3 months intervention period

Assessing the effect of the intervention on C-reactive Protein(mg/L) which is a blood marker for systemic inflammation. High CRP values indicate systemic inflammation.

Time frame: 3 months

Change in alpha-1-acid glycoprotein (AGP) over the 3 months intervention period

Assessing the effect of the intervention on alpha-1-acid glycoprotein (g/L) which is a blood marker for systemic inflammation. High AGP values indicate systemic inflammation.

Time frame: 3 months

Change in insulin like growth factor (IGF-1) over the 3 months intervention period

Assessing the effect of the intervention on insulin like growth factor (ng/mL) which is a blood markers for growth. High IGF-1 values support growth.

Time frame: 3 months

Change in hemoglobin over the 3 months intervention period

Assessing the effect of the intervention on hemoglobin measured in g/dL. Low hemoglobin levels indicate Anemia.

Time frame: 3 months

Change in ferritin over the 3 months intervention period

Assessing the effect of the intervention on serum ferritin measured in μg/L. A low level of serum ferritin indicates Anemia.

Time frame: 3 months

Change in soluble transferrin receptor (sTfR) over the 3 months intervention period

Assessing the effect of the intervention on soluble transferrin receptor measured in mg/L. A high level of sTfR is associated with Anemia.

Time frame: 3 months

Change in cobalamin over the 3 months intervention period

Assessing the effect of the intervention on cobalamin measured in pmol/L. A low level of cobalamin is associated with Vitamin B12 deficiency.

Time frame: 3 months

Change in retinol binding protein (RBP) over the 3 months intervention period

Assessing the effect of the intervention on serum retinol binding protein (RBP) measured in µmol/l. A low level of RBP is associated with Vitamin A deficiency.

Time frame: 3 months

Change in methyl malonic acid (MMA) over the 3 months intervention period

Assessing the effect of the intervention on methyl malonic acid (MMA) measured in nmol/L. A high level of MMA indicates Vitamin B12 deficiency.

Time frame: 3 months

Change in citrulline over the 3 months intervention period

Assessing the effect of the intervention on plasma citrulline measured in μmol/L. A low level of citrulline indicates impaired intestinal function.

Time frame: 3 months