Thoracoscopic Talc Pleurodesis Versus Bleomycin -Tranxemic Acid Mixture Injection in Chest Tube in Malignant Pleural Effusion

Mohamed Sabry60 enrolled

Overview

Comparing Two Methods to Treat Fluid Build-up in Chest for Cancer Patients:Talc Powder Surgery versus Chest Tube Medicine.

Closure of the space where the effusion is recurrently accumulated through talc poudrage in thoracoscopy or bleomycin - tranxemic acid solution injection in chest tube.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Malignant Pleural Effusions (Mpe)- Pleurodesis Pleurodesis

Interventions

thoracoscopePROCEDURE

bleomycin- tranxemic acid mixture pleurodesis versus thoracoscopic talc poudrage

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: \- 1. Adult patients (more than 18 years) with malignant pleural effusion or highly suspected exudate. 2\. Fit patients for the procedure selected. Exclusion Criteria: 1. Inability to provide informed consent for the procedure. 2. Hemodynamically unstable patients. 3. Bleeding diathesis. 4. Uncontrolled cough. 5. Hypoxic index less than 300. 6. Endobronchial obstruction. 7. Pleural thickening with trapped lung.

Locations (1)

Chest Department -Faculty of Medicine

Alexandria, Azarita, Egypt

Outcomes

Primary Outcomes

Dyspnea Borg Scale

the rate of shortness of breath from number 0 to number 10

Time frame: one month

Data from ClinicalTrials.gov

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