Low-dose Neostigmine at TOF Ratio of 0.7 Improves Neuromuscular Recovery

Seoul National University Hospital59 enrolled

Overview

This study is a prospective observational study. A total of 54 patients were included in this study. We observed the time from neostigmine administration to TOF ratio of 1.0.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Recovery Time

Interventions

Neostigmine + GlycopyrrolateDRUG

a 20 mcg/kg of neostigmine and 4 mcg/kg of glycopyrrolate were administered at a TOF ratio of 0.7.

Eligibility

Sex: ALLMin age: 20 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients undergoing elective thyroid surgery under general anesthesia * a body mass index of 18.5-25 kg/m2 * Age ≥ 20 Exclusion Criteria: * Refused to participate * history of hypersensitivity to acetylcholinesterase inhibitor * neuromuscular disease * hepatic or renal dysfunction

Locations (1)

Seoul National University Bundang Hospital

Seongnam, South Korea

Outcomes

Primary Outcomes

Recovery time

Time from neostigmine administration to TOF ratio of 1.0

Time frame: During surgery

Data from ClinicalTrials.gov

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