Evolution of Intracardiac Electrograms Recorded by Left Bundle Branch Pacing Lead in Patients With ICD or CRT-D

Medtronic Cardiac Rhythm and Heart Failure50 enrolled

Overview

The goal of this observational study is to investigate the changes of LBB EGM during daily activities and overdrive pacing at the time of peri-implantation and up to 6-month follow-ups of ICD/CRT-D patients. The main question it aims to answer is: • Does the LBBP lead can provide accurate, stable, and valid EGM for ICD/CRT-D sensing and detection of ventricular tachyarrhythmia events? In each patient intracardiac EGMs of LBBP lead will be collected by ambulatory Holter monitor at the time of peri-implantation and up to 6-month follow-up. EGM collection will be collected at resting and walking conditions and overdrive pacing.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Ventricular Tachycardia (VT)Ventricular Fibrillation

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients aged \>=18 yrs. * Patients indicated for ICD or CRT-D (primary or secondary prevention) * Patients who recently (\<=30 days) received ICD/CRT-D implantation with LBBP * Patients' EGM can be digitally recorded * Patients are willing to participate in the study and provide signed informed consent Exclusion Criteria: * Patients received CIED upgrade or replacement with old pacing leads * Patients are pregnant * Patients participate in another study that will confound this study

Locations (2)

Outcomes

Primary Outcomes

R-wave amplitude of LBB EGM

Amplitude in millivolt

Time frame: At the enrollment, 3 months after enrollment and 6 months after enrollment

Secondary Outcomes

EGM morphology-LVAT

LVAT in millisecond, calculated based on electrogram recorded by LBB lead