The study included 21 adult participants, aged 19-46 years (19 female participants and 2 male participants). The selection criteria included the following parameters: Body Mass Index (BMI), calculated as weight (kg) divided by height squared (m²), between 18.5 and 29.99; Waist-to-Hip Ratio with thresholds set at \>0.90 for males and \>0.85 for females for individuals with normal weight (eutrophic); percentage of body fat: Considered within normal range if \<30% for individuals with normal weight. Standard biochemical and anthropometric measurements were carried out to all the subjects.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
21
Probiotic
Fecal flora cultures (Count of colonies/mL)
Relative amount of colonies (CFU) of Escherichia coli, Clostridium species and Lactobacillus
Time frame: From enrollment to the end of treatment at 45 days weeks, every 15 days
Serum immunoglobulins
Serum concentration of G, A, M, and G subclasses, as well as the complement C3 and C4 factors,
Time frame: From enrollment to the end of treatment at 45 days weeks, every 15 days
Lymphocyte Subpopulations
Concentration of T Lymphocytes: CD3, CD4, CD8, CD45 RA, and CD45 RO (distinguishing between helper T cells, cytotoxic T cells, and naïve or memory subsets within each group). ii) B Lymphocytes: CD19; iii) NK Cells: CD16 and CD56.
Time frame: From enrollment to the end of treatment at 45 days weeks, every 15 days
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