This study evaluates the effects of intrathecal midazolam (1 mg) combined with hyperbaric bupivacaine 0.5% (15 mg) for spinal anesthesia in cesarean section patients.
The addition of midazolam, a benzodiazepine with analgesic and anxiolytic properties to bupivacaine is hypothesized to enhance the quality of anesthesia and postoperative pain relief without significant side effects. A comparative analysis was conducted to assess sensory and motor block characteristics, postoperative analgesia duration, maternal hemodynamic stability, and neonatal outcomes.
Study Type
OBSERVATIONAL
Enrollment
64
A comparative analysis was conducted to assess sensory and motor block characteristics, postoperative analgesia duration, maternal hemodynamic stability, and neonatal outcomes. Results demonstrated that intrathecal midazolam significantly prolonged postoperative analgesia and reduced analgesic requirements while maintaining hemodynamic stability and maternal-neonatal safety. This combination provides a potential enhancement to spinal anesthesia techniques, improving maternal comfort and overall perioperative outcomes in obstetric patients.
Nowshera
Nowshera, Khyber Pakhtunkhwa, Pakistan
Duration of postoperative analgesia
Time from intrathecal drug administration to the first request for additional analgesia by the patient.
Time frame: 12 Months
Quality of sensory and motor block
Onset, level, and duration of sensory block, Onset and duration of motor block, Maximum sensory block level achieved.
Time frame: 12 Months
Hemodynamic stability
Incidence and severity of hypotension, bradycardia, or other hemodynamic changes during the perioperative period.
Time frame: 12 months
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