DAANCE FOR CHEMOTHERAPY-INDUCED NEUROPATHY

Patient-Reported Outcome (PRO) - hot/cold sensation

Sensation of hot and/or cold (11 point Likert scale).

Time frame: 4 weeks; 8 weeks; 12 weeks

EORTC-CIPN 20

European Organization for Research and Treatment of Cancer Chemotherapy-Induced Peripheral Neuropathy symptoms inventory (CIPN 20),

Time frame: mid-intervention (4weeks); post -intervention (8 weeks); 1 month follow up post intervention

Brief Fatigue Inventory

The Brief Fatigue Inventory (BFI) is a short questionnaire used to quickly assess the severity of fatigue, particularly in cancer patients, by measuring both the level of tiredness and how much fatigue interferes with daily activities, allowing for rapid evaluation in clinical settings or research studies; it consists of nine items where patients rate their fatigue on a scale from 0 to 10, with higher scores indicating greater fatigue severity.

Time frame: 4 weeks; 8 weeks; 12 weeks

Brief Pain Inventory

The Brief Pain Inventory (BPI) is a self-reported questionnaire used to assess the severity of pain and how much it interferes with a person's daily activities, including aspects like mood, work, sleep, and social interactions. It measures pain intensity on a scale from 0 (no pain) to 10 (worst pain imaginable) across different timeframes (current, average, worst pain) while also evaluating the impact of pain on various life functions on a similar 0-10 scale; it comes in both short and long forms, with the long form including more detailed questions about pain characteristics and treatment history.

Time frame: 4 weeks; 8 weeks; 12 weeks

Patient Reported Outcomes version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE)

The PRO-CTCAE assessment, which stands for "Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events," is a measurement system designed by the National Cancer Institute (NCI) to capture and evaluate the symptomatic side effects experienced by cancer patients during clinical trials, allowing patients to self-report on the frequency, severity, interference, and presence/absence of symptoms like pain, fatigue, nausea, and skin reactions, providing a more patient-centric perspective on treatment toxicity compared to clinician-based assessments alone.

Time frame: 4 weeks; 8 weeks; 12 weeks

Physical Health Questionnaire-2 (PHQ-2)

The PHQ-2 asks how often a patient has experienced depressed mood or anhedonia in the last two weeks

Time frame: 4 weeks; 8 weeks; 12 weeks

Generalized Anxiety Questionnaire

Each question has a 4-point scale, ranging from 1, "not at all", to 4, "nearly every day".

Time frame: 4 weeks; 8 weeks; 12 weeks

Falls

Report of whether you have fallen or lost your balanced since we last spoke with you

Time frame: 4 weeks; 8 weeks; 12 weeks; 6 months following intervention end

The Mini Balance Evaluation Systems Test (MiniBEST)

The Mini-BESTest (Balance Evaluation Systems Test) is a 14-item test that measures balance, functional mobility, and gait by assessing dynamic balance, anticipatory postural adjustments, reactive postural control, sensory orientation, and dynamic gait.

Time frame: 4 weeks (Control group); 8 weeks (Intervention group)

Biomechanical measures of postural control

Postural sway while standing still with eyes closed.

Time frame: 4 weeks; 8 weeks; 12 weeks

Six minute walk test (6mwt)

A "6 minute walk test" (6MWT) is a medical assessment where a person walks as far as they can in a designated area for six minutes, with the primary goal of measuring their functional exercise capacity, usually used to evaluate patients with conditions affecting their breathing or mobility, like heart failure or lung disease; the distance walked during those six minutes is the key measurement recorded as the "6-minute walk distance" (6MWD)

Time frame: 4 weeks; 8 weeks

Gait stability

Stability between gait strides over the period of the 6mwt.

Time frame: 4 weeks; 8 weeks

Upper Extremity Function

We assess upper extremity function using the "back scratch test" which measures upper body flexibility and shoulder mobility. Participants reach both hands toward each other behind their backs and staff measure the distance remaining between their fingertips.

Time frame: 4 weeks; 8 weeks; 12 weeks