Accuracy of Automatic Contusion Volume Scanning for Predicting the Incidence of Pneumonia in Patients With Thoracic Trauma

Azienda Usl di Bologna486 enrolled

Overview

The goal of this retrospective observational study is to evaluate the diagnostic accuracy of pulmonary contusion volume in predicting early pneumonia in patients with thoracic trauma. The primary question we aim to answer is: What is the diagnostic accuracy of pulmonary contusion volume in predicting pneumonia within 7 days post-trauma? Moreover, we aim to explore which is the overlap between the contused segments and those developing pneumonia. Finally, we aim to explore relevant differences in radiomic features between contused segments that developed pneumonia.

Study Type

OBSERVATIONAL

Enrollment

486

Conditions

Pneumonia Thoracic Trauma

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Admission to the ED for trauma as primary diagnosis * Whole-body contrast CT scan performed within 6 hours from admission Exclusion Criteria: * Age \<18 years

Locations (1)

Maggiore Hospital Carlo Alberto Pizzardi

Bologna, BO, Italy

Outcomes

Primary Outcomes

7d-pneumonia

Pneumonia appearing within 7 days from trauma, defined as: • New or worsening pulmonary infiltrates plus ≥ 2 of the following: * Body temperature ≥ 38°C or ≤ 35°C * White Blood Cell (WBC) count \> 12,000 or \< 4,000 cells/mL or presence of immature granulocytes in the blood sample * Purulent sputum * Worsening pulmonary oxygenation, defined as a decline in the PaO2/FiO2 ratio

Time frame: 7 days