Changes in FeNO Value During Pulmonary Rehabilitation in Patients with Asthma

Schön Klinik Berchtesgadener Land62 enrolled

Overview

This study investigates the use of fractional exhaled nitric oxide (FeNO) measurement to monitor non-pharmacological therapy during a three-week inpatient rehabilitation programme for asthma patients. It compares FeNO levels (measured three times a day) with clinical parameters and quality of life to analyse daily fluctuations and the acute effect of exercise training on FeNO levels. As FeNO is a non-invasive biomarker of airway inflammation, this study aims to expand its role in therapy monitoring and explore its application in a rehabilitation setting.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Asthma Bronchiale Asthmatic Patients Asthmatics

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * confirmed diagnosis of bronchial asthma (all disease severities) * Chronic Obstructive Pulmonary Disease (COPD) with an asthma component, where the asthma component plays a clinically relevant role * written informed consent Exclusion Criteria: * Chronic Obstructive Pulmonary Disease (COPD) as the primary disease * unability to perform FeNO measurement independently

Locations (1)

Outcomes

Primary Outcomes

Fractional Exhaled Nitric Oxide (FeNO) at rest

Measurement of FeNo will be done with the Vivatmo Me device (by Bosch Health Care Solutions GmbH)

Time frame: From enrollment to the end of rehabilitation at 3 weeks. Daily measurements at 9AM; 1PM; 5PM

Fractional Exhaled Nitric Oxide (FeNO) before/after exercise

Measurement of FeNo will be done with the Vivatmo Me device (by Bosch Health Care Solutions GmbH)

Time frame: From enrollment to the end of rehabilitation at 3 weeks, FeNO measurements will be done before and after a bicycle endurance training