Renal Resistive Index as an Indicator of Lupus Nephritis Severity and Systemic Lupus Activity

Kasr El Aini Hospital75 enrolled

Overview

The study explores the role of the colour Doppler scanning of the renal arteries and its relation to the degree of disease affection in lupus nephritis

we have recruited patients into 3 groups The first group is patients with lupus nephritis The second groups is patients with systemic lupus erythromatosus without nephritis The third groups is normal healthy controls we explored the association of colour Doppler and the renal resistive index with the degree of the renal affection in lupus nephritis

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

Systemic Lupus Erthematosus Lupus Glomerulonephritis Lupus Flare

Interventions

colour doppler of the renal artery and measurement of resistive indexDIAGNOSTIC_TEST

using colour doppler to asses vascular resistance and resistive index

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * 1\. Systemic lupus erythematosus. 2. Lupus nephritis. 3. Adults \>18 years old. Exclusion Criteria: * 1\. End Stage Renal Disease. 2. Diabetes Mellitus. 3. Heart failure. 4. Hepatic diseases. 5. Obstructive nephropathy. 6. Renal artery stenosis or occlusion.

Locations (1)

Cairo University Hospitals

Cairo, Egypt

Outcomes

Primary Outcomes

Resistive index

The resistive index of the renal arteries as measured by the colour Doppler

Time frame: At the time of recruitment

Data from ClinicalTrials.gov

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