Assessment of Pulmonary Function in Relation to the Anesthetic Used in Patients Undergoing Bariatric Surgery

Medical University of Gdansk100 enrolled

Overview

It is known that more or less pronounced impairment of pulmonary function occurs after anesthesia. It has been demonstrated in the postoperative period in both patients undergoing general and regional anesthesia, in patients after intra-abdominal and superficial procedures, in overweight and normal-weight patients. It has also been shown that when general anesthesia is performed with the inhalation anesthetic sevoflurane, there is a slightly smaller reduction in lung function parameters than when only intravenous anesthetics are used. The purpose of this study is to evaluate lung function before induction and after awakening from general anesthesia depending on the inhalational anesthetic used in obese patients undergoing bariatric surgery

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

OTHER

Masking

NONE

Enrollment

100

Conditions

Obesity and Obesity-related Medical Conditions

Interventions

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Obese patients qualified for bariatric surgery. Exclusion Criteria: * Patients who have absolute contraindications to spirometry testing, i.e: * with aneurysms of the aorta or cerebral arteries threatening to rupture, after recent vascular surgery * with increased intracranial pressure, after recent intracranial bleeding or head surgery within the cranial cavity * after acute conditions within 6 months prior to surgery such as stroke, myocardial infarction, unstable angina, pneumothorax * with uncontrolled hypertension * after recent eye surgery or a history of retinal detachment * with hemoptysis of unknown etiology. And patients unable to perform spirometry testing

Outcomes

Primary Outcomes

Heart rate (HR)

HR will be measured by ecg in beat per minute

Time frame: Continuously during whole duration of anesthesia

Pulse oximetry (SpO2)

SpO2 will be measured by light spectrometry percutaneous sensor in %

Time frame: Continuously during whole duration of anesthesia

End tidal CO2 (etCO2)

etCO2 will be measured by capnography with infrared radiation sensor in mmHg. Sensor will be attached to breathing circuit.

Time frame: Continuously during whole duration of anesthesia

Minimum alveolar concentration (MAC)

MAC will be measured based on exhaled anesthetic gas concentration in absolute numbers

Time frame: Continuously during whole duration of anesthesia

Bispectral index (BIS)

BIS will be measured with Covidien BIS monitoring system in absolute numbers

Time frame: Continuously during whole duration of anesthesia

Train of for (TOF)

TOF will be measured in absolute numbers

Time frame: Every 2.5 minutes during whole duration of anesthesia

Non invasive blood pressure (NIBP)

NIBP will be measured with oscillometric method in mmHG

Time frame: Every 5 minutes during whole duration of anesthesia

Forced vital capacity (FVC)

FVC will be measured with spirometry