The aim was to examine the effectiveness of hypochlorous acid on postoperative wound healing in 24 systemically healthy gingivectomy participants aged 12-30. The participants were divided into 3 groups as hypochlorous acid group, chlorhexidine group and saline group and their wound healing was evaluated on the 1st, 3rd and 7th days.
The aim of this study was to investigate the effectiveness of hypochlorous acid on postoperative wound healing in 24 participants aged 12-30 who underwent gingivectomy involving the 6 anterior teeth of the upper or lower jaw with chronic inflammatory gingival overgrowth. The participants were divided into 3 groups as hypochlorous acid group, chlorhexidine group and saline group and were called for control on the 1st, 3rd and 7th days to evaluate wound healing. Periodontal indexes, visual analog scale (VAS), H2O2, plaque staining agent test, and histological analyzes were used to evaluate wound healing. The data were analyzed statistically.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
24
Hypochlorous acid, chlorhexidine and saline groups were compared as postoperative gargles after gingivectomy surgery.
Atatürk University Faculty of Dentistry
Erzurum, Turkey (Türkiye)
Plaque index
The amount of plaque was scored.
Time frame: Baseline, Day 7
Gingival index
The gingival status was scored.
Time frame: Baseline, Day 7
Probing depth
The periodontal pocket depth was performed (mm).
Time frame: Baseline, Day 7
Clinical attachment level
The clinical attachment level was measured (mm).
Time frame: Baseline, Day 7
Bleeding on probing
The gingival status was scored.(%)
Time frame: Baseline, Day 7
Epithelialization with plaque staining agent
The wound surface epithelialization was observed with plaque staining agent. The wound surface was stained with plaque staining dye and the dark colored area is calculated as mm2.
Time frame: Day 1, 3, and 7
Epithelialization with H2O2
The wound surface epithelialization was observed with H2O2. Scored as foaming present/absent after application with H2O2
Time frame: Day 3 and 7
Histological analysis
Histological analysis evaluated epithelial keratinization, regeneration, and/or degeneration during the healing process and to obtain epithelial samples repeatedly. The number of keratinocytes was counted.
Time frame: Day 1, 3, and 7
postoperative pain with Visiual Analogue Scale (VAS)
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VAS scores were taken on the 3rd and 7th days without any intervention to the patient. Scored between 1-10 as 1 was no pain, 10 was pain.
Time frame: Day 3 and 7