The goal of this clinical trial is to compare the effectiveness of the thoracolumbar interfascial plane block (TLIP block) versus local anesthetic (LA) infiltration in managing postoperative pain in minimally invasive surgery (MIS) for spine surgery. The primary outcome was total morphine consumption. Secondary outcomes included pain scores using the the numerical verbal scale (NRS), opioid-related side effects, time of the first request for rescue analgesia, time to ambulation and hospital length of stay.
A single-center, prospective, double-blind, randomized controlled trial at Queen Savang Vadhana Memorial Hospital. All 40 enrolled patients were randomized to receive the assigned intervention, Thoracolumbar interfascial plane group (TLIP group) and local anesthetic (LA) infiltration group (LA group). * For TLIP group, patients will receive ultrasound-guild bilateral TLIP block with a total of 40 ml of 0.25% Bupivacaine. * For LA group, patients will receive local anesthetic infiltration with a same drug by orthopedic surgeon. At the end of surgery, patients were extubated and transferred to the PACU before being shifted to the orthopedic ward. Postoperative assessments began upon admission to the PACU, designated as time zero, and continued at regular intervals in the orthopedic ward (6-, 8-, 12- and 24-hours post-surgery).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
40
Ultrasound-guild bilateral Thoracolumbar interfascial plane block with a total 40 ml, 0.25% bupivacaine by anesthesiologist
0.25%bupivacaine infiltration at surgical wound site by orthopedic surgeon
Queen Savang Vadhana Memorial Hospital
Chon Buri, Changwat Chon Buri, Thailand
Total morphine consumption
Total doses of morphine requirement during first 24 hours postoperative period (The investigators recorded at 6,8,12 and 24 hours, postoperatively)
Time frame: 24 hours
Pain score (NRS)
The investigators recorded pain score at 6,8,12, 24 hours postoperatively. The scale ranges from 0 to 10, where 0 represents the lowest score and 10 represents the highest score
Time frame: 24 hours
Postoperative nausea and vomiting
The investigators recorded the occurrence of postoperative nausea and vomiting (PONV) as present or absent.
Time frame: 24 hours
Length of hospital stay
The investigators recorded the number of hospital days from admission to discharge.
Time frame: 2 weeks
Time of the first request for rescue analgesia
Time when a patient first asks for pain relief after their surgery.
Time frame: 24 hours
Respiratory depression
The investigators recorded the occurrence of respiratory depression as present or absent.
Time frame: 24 hours
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